Document (#30258)

Author
Fenstermacher, D.A.
Title
Introduction to bioinformatics.
Source
Journal of the American Society for Information Science and Technology. 56(2005) no.5, S.440-446
Year
2005
Abstract
Bioinformatics is a multifaceted discipline combining many scientific fields including computational biology, statistics, mathematics, molecular biology, and genetics. Bioinformatics enables biomedical investigators to exploit existing and emerging computational technologies to seamlessly store, mine, retrieve, and analyze data from genomics and proteomics technologies. This is achieved by creating unified data models, standardizing data interfaces, developing structured vocabularies, generating new data visualization methods, and capturing detailed metadata that describes various aspects of the experimental design and analysis methods. Already there are a number of related undertakings that are dividing the field into more specialized groups. Clinical Bioinformatics and Biomedical Informatics are emerging as transitional fields to promote the utilization of genomics and proteomics data combined with medical history and demographic data towards personalized medicine, molecular diagnostics, pharmacogenomics and predicting outcomes of therapeutic interventions. The field of bioinformatics will continue to evolve through the incorporation of diverse technologies and methodologies that draw experts from disparate fields to create the latest computational and informational tools specifically design for the biomedical research enterprise.
Footnote
Beitrag in einem special issue on bioinformatics

Similar documents (content)

  1. Song, M.; Kim, S.Y.; Zhang, G.; Ding, Y.; Chambers, T.: Productivity and influence in bioinformatics : a bibliometric analysis using PubMed central (2014) 0.31
    0.3076932 = sum of:
      0.3076932 = product of:
        1.2820551 = sum of:
          0.05031765 = weight(abstract_txt:field in 2202) [ClassicSimilarity], result of:
            0.05031765 = score(doc=2202,freq=4.0), product of:
              0.07174726 = queryWeight, product of:
                1.1998022 = boost
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.013322959 = queryNorm
              0.7013181 = fieldWeight in 2202, product of:
                2.0 = tf(freq=4.0), with freq of:
                  4.0 = termFreq=4.0
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.078125 = fieldNorm(doc=2202)
          0.07597643 = weight(abstract_txt:emerging in 2202) [ClassicSimilarity], result of:
            0.07597643 = score(doc=2202,freq=2.0), product of:
              0.118974626 = queryWeight, product of:
                1.5450201 = boost
                5.779889 = idf(docFreq=372, maxDocs=44421)
                0.013322959 = queryNorm
              0.63859355 = fieldWeight in 2202, product of:
                1.4142135 = tf(freq=2.0), with freq of:
                  2.0 = termFreq=2.0
                5.779889 = idf(docFreq=372, maxDocs=44421)
                0.078125 = fieldNorm(doc=2202)
          0.19405276 = weight(abstract_txt:genomics in 2202) [ClassicSimilarity], result of:
            0.19405276 = score(doc=2202,freq=1.0), product of:
              0.28008613 = queryWeight, product of:
                2.37057 = boost
                8.868255 = idf(docFreq=16, maxDocs=44421)
                0.013322959 = queryNorm
              0.6928324 = fieldWeight in 2202, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                8.868255 = idf(docFreq=16, maxDocs=44421)
                0.078125 = fieldNorm(doc=2202)
          0.053395927 = weight(abstract_txt:data in 2202) [ClassicSimilarity], result of:
            0.053395927 = score(doc=2202,freq=3.0), product of:
              0.118490584 = queryWeight, product of:
                2.6706042 = boost
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.013322959 = queryNorm
              0.45063436 = fieldWeight in 2202, product of:
                1.7320508 = tf(freq=3.0), with freq of:
                  3.0 = termFreq=3.0
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.078125 = fieldNorm(doc=2202)
          0.15106796 = weight(abstract_txt:biomedical in 2202) [ClassicSimilarity], result of:
            0.15106796 = score(doc=2202,freq=1.0), product of:
              0.27132538 = queryWeight, product of:
                2.8575761 = boost
                7.1267567 = idf(docFreq=96, maxDocs=44421)
                0.013322959 = queryNorm
              0.55677783 = fieldWeight in 2202, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                7.1267567 = idf(docFreq=96, maxDocs=44421)
                0.078125 = fieldNorm(doc=2202)
          0.7572444 = weight(abstract_txt:bioinformatics in 2202) [ClassicSimilarity], result of:
            0.7572444 = score(doc=2202,freq=3.0), product of:
              0.6532941 = queryWeight, product of:
                5.7244177 = boost
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.013322959 = queryNorm
              1.1591172 = fieldWeight in 2202, product of:
                1.7320508 = tf(freq=3.0), with freq of:
                  3.0 = termFreq=3.0
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.078125 = fieldNorm(doc=2202)
        0.24 = coord(6/25)
    
  2. Jonkers, K.; Moya Anegon, F. de; Aguillo, I.F.: Measuring the usage of e-research infrastructure as an indicator of research activity (2012) 0.25
    0.24801761 = sum of:
      0.24801761 = product of:
        0.8857772 = sum of:
          0.019792413 = weight(abstract_txt:methods in 1277) [ClassicSimilarity], result of:
            0.019792413 = score(doc=1277,freq=1.0), product of:
              0.06114265 = queryWeight, product of:
                1.1075902 = boost
                4.1434727 = idf(docFreq=1915, maxDocs=44421)
                0.013322959 = queryNorm
              0.3237088 = fieldWeight in 1277, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                4.1434727 = idf(docFreq=1915, maxDocs=44421)
                0.078125 = fieldNorm(doc=1277)
          0.025158824 = weight(abstract_txt:field in 1277) [ClassicSimilarity], result of:
            0.025158824 = score(doc=1277,freq=1.0), product of:
              0.07174726 = queryWeight, product of:
                1.1998022 = boost
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.013322959 = queryNorm
              0.35065904 = fieldWeight in 1277, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.078125 = fieldNorm(doc=1277)
          0.10353959 = weight(abstract_txt:genetics in 1277) [ClassicSimilarity], result of:
            0.10353959 = score(doc=1277,freq=1.0), product of:
              0.1462422 = queryWeight, product of:
                1.2112348 = boost
                9.06241 = idf(docFreq=13, maxDocs=44421)
                0.013322959 = queryNorm
              0.7080008 = fieldWeight in 1277, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                9.06241 = idf(docFreq=13, maxDocs=44421)
                0.078125 = fieldNorm(doc=1277)
          0.099849224 = weight(abstract_txt:biology in 1277) [ClassicSimilarity], result of:
            0.099849224 = score(doc=1277,freq=1.0), product of:
              0.17984907 = queryWeight, product of:
                1.8995953 = boost
                7.1063476 = idf(docFreq=98, maxDocs=44421)
                0.013322959 = queryNorm
              0.5551834 = fieldWeight in 1277, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                7.1063476 = idf(docFreq=98, maxDocs=44421)
                0.078125 = fieldNorm(doc=1277)
          0.052895494 = weight(abstract_txt:fields in 1277) [ClassicSimilarity], result of:
            0.052895494 = score(doc=1277,freq=1.0), product of:
              0.13478905 = queryWeight, product of:
                2.0140948 = boost
                5.0231256 = idf(docFreq=794, maxDocs=44421)
                0.013322959 = queryNorm
              0.39243168 = fieldWeight in 1277, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                5.0231256 = idf(docFreq=794, maxDocs=44421)
                0.078125 = fieldNorm(doc=1277)
          0.14734635 = weight(abstract_txt:molecular in 1277) [ClassicSimilarity], result of:
            0.14734635 = score(doc=1277,freq=1.0), product of:
              0.2331156 = queryWeight, product of:
                2.1626818 = boost
                8.090549 = idf(docFreq=36, maxDocs=44421)
                0.013322959 = queryNorm
              0.6320742 = fieldWeight in 1277, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                8.090549 = idf(docFreq=36, maxDocs=44421)
                0.078125 = fieldNorm(doc=1277)
          0.43719527 = weight(abstract_txt:bioinformatics in 1277) [ClassicSimilarity], result of:
            0.43719527 = score(doc=1277,freq=1.0), product of:
              0.6532941 = queryWeight, product of:
                5.7244177 = boost
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.013322959 = queryNorm
              0.66921663 = fieldWeight in 1277, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.078125 = fieldNorm(doc=1277)
        0.28 = coord(7/25)
    
  3. Toldo, L.; Rippmann, F.: Integrated bioinformatics application for automated target discovery. (2005) 0.18
    0.1771282 = sum of:
      0.1771282 = product of:
        0.885641 = sum of:
          0.019792413 = weight(abstract_txt:methods in 260) [ClassicSimilarity], result of:
            0.019792413 = score(doc=260,freq=1.0), product of:
              0.06114265 = queryWeight, product of:
                1.1075902 = boost
                4.1434727 = idf(docFreq=1915, maxDocs=44421)
                0.013322959 = queryNorm
              0.3237088 = fieldWeight in 260, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                4.1434727 = idf(docFreq=1915, maxDocs=44421)
                0.078125 = fieldNorm(doc=260)
          0.052895494 = weight(abstract_txt:fields in 260) [ClassicSimilarity], result of:
            0.052895494 = score(doc=260,freq=1.0), product of:
              0.13478905 = queryWeight, product of:
                2.0140948 = boost
                5.0231256 = idf(docFreq=794, maxDocs=44421)
                0.013322959 = queryNorm
              0.39243168 = fieldWeight in 260, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                5.0231256 = idf(docFreq=794, maxDocs=44421)
                0.078125 = fieldNorm(doc=260)
          0.043597594 = weight(abstract_txt:data in 260) [ClassicSimilarity], result of:
            0.043597594 = score(doc=260,freq=2.0), product of:
              0.118490584 = queryWeight, product of:
                2.6706042 = boost
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.013322959 = queryNorm
              0.3679414 = fieldWeight in 260, product of:
                1.4142135 = tf(freq=2.0), with freq of:
                  2.0 = termFreq=2.0
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.078125 = fieldNorm(doc=260)
          0.15106796 = weight(abstract_txt:biomedical in 260) [ClassicSimilarity], result of:
            0.15106796 = score(doc=260,freq=1.0), product of:
              0.27132538 = queryWeight, product of:
                2.8575761 = boost
                7.1267567 = idf(docFreq=96, maxDocs=44421)
                0.013322959 = queryNorm
              0.55677783 = fieldWeight in 260, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                7.1267567 = idf(docFreq=96, maxDocs=44421)
                0.078125 = fieldNorm(doc=260)
          0.6182875 = weight(abstract_txt:bioinformatics in 260) [ClassicSimilarity], result of:
            0.6182875 = score(doc=260,freq=2.0), product of:
              0.6532941 = queryWeight, product of:
                5.7244177 = boost
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.013322959 = queryNorm
              0.9464153 = fieldWeight in 260, product of:
                1.4142135 = tf(freq=2.0), with freq of:
                  2.0 = termFreq=2.0
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.078125 = fieldNorm(doc=260)
        0.2 = coord(5/25)
    
  4. Shachak, A.; Fine, S.: ¬The Effect of training on biologists acceptance of bioinformatics tools : a field experiment (2008) 0.17
    0.16847767 = sum of:
      0.16847767 = product of:
        1.0529854 = sum of:
          0.01893584 = weight(abstract_txt:design in 2606) [ClassicSimilarity], result of:
            0.01893584 = score(doc=2606,freq=2.0), product of:
              0.05467618 = queryWeight, product of:
                1.0473843 = boost
                3.9182436 = idf(docFreq=2399, maxDocs=44421)
                0.013322959 = queryNorm
              0.34632707 = fieldWeight in 2606, product of:
                1.4142135 = tf(freq=2.0), with freq of:
                  2.0 = termFreq=2.0
                3.9182436 = idf(docFreq=2399, maxDocs=44421)
                0.0625 = fieldNorm(doc=2606)
          0.02012706 = weight(abstract_txt:field in 2606) [ClassicSimilarity], result of:
            0.02012706 = score(doc=2606,freq=1.0), product of:
              0.07174726 = queryWeight, product of:
                1.1998022 = boost
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.013322959 = queryNorm
              0.28052723 = fieldWeight in 2606, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.0625 = fieldNorm(doc=2606)
          0.024662523 = weight(abstract_txt:data in 2606) [ClassicSimilarity], result of:
            0.024662523 = score(doc=2606,freq=1.0), product of:
              0.118490584 = queryWeight, product of:
                2.6706042 = boost
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.013322959 = queryNorm
              0.20813909 = fieldWeight in 2606, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.0625 = fieldNorm(doc=2606)
          0.98926 = weight(abstract_txt:bioinformatics in 2606) [ClassicSimilarity], result of:
            0.98926 = score(doc=2606,freq=8.0), product of:
              0.6532941 = queryWeight, product of:
                5.7244177 = boost
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.013322959 = queryNorm
              1.5142645 = fieldWeight in 2606, product of:
                2.828427 = tf(freq=8.0), with freq of:
                  8.0 = termFreq=8.0
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.0625 = fieldNorm(doc=2606)
        0.16 = coord(4/25)
    
  5. Huang, H.; Andrews, J.; Tang, J.: Citation characterization and impact normalization in bioinformatics journals (2012) 0.15
    0.15037356 = sum of:
      0.15037356 = product of:
        0.9398348 = sum of:
          0.02012706 = weight(abstract_txt:field in 1069) [ClassicSimilarity], result of:
            0.02012706 = score(doc=1069,freq=1.0), product of:
              0.07174726 = queryWeight, product of:
                1.1998022 = boost
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.013322959 = queryNorm
              0.28052723 = fieldWeight in 1069, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                4.4884357 = idf(docFreq=1356, maxDocs=44421)
                0.0625 = fieldNorm(doc=1069)
          0.1129665 = weight(abstract_txt:biology in 1069) [ClassicSimilarity], result of:
            0.1129665 = score(doc=1069,freq=2.0), product of:
              0.17984907 = queryWeight, product of:
                1.8995953 = boost
                7.1063476 = idf(docFreq=98, maxDocs=44421)
                0.013322959 = queryNorm
              0.62811834 = fieldWeight in 1069, product of:
                1.4142135 = tf(freq=2.0), with freq of:
                  2.0 = termFreq=2.0
                7.1063476 = idf(docFreq=98, maxDocs=44421)
                0.0625 = fieldNorm(doc=1069)
          0.024662523 = weight(abstract_txt:data in 1069) [ClassicSimilarity], result of:
            0.024662523 = score(doc=1069,freq=1.0), product of:
              0.118490584 = queryWeight, product of:
                2.6706042 = boost
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.013322959 = queryNorm
              0.20813909 = fieldWeight in 1069, product of:
                1.0 = tf(freq=1.0), with freq of:
                  1.0 = termFreq=1.0
                3.3302255 = idf(docFreq=4320, maxDocs=44421)
                0.0625 = fieldNorm(doc=1069)
          0.7820787 = weight(abstract_txt:bioinformatics in 1069) [ClassicSimilarity], result of:
            0.7820787 = score(doc=1069,freq=5.0), product of:
              0.6532941 = queryWeight, product of:
                5.7244177 = boost
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.013322959 = queryNorm
              1.1971312 = fieldWeight in 1069, product of:
                2.236068 = tf(freq=5.0), with freq of:
                  5.0 = termFreq=5.0
                8.565973 = idf(docFreq=22, maxDocs=44421)
                0.0625 = fieldNorm(doc=1069)
        0.16 = coord(4/25)