Document (#30258)

Author

Fenstermacher, D.A.

Title

Introduction to bioinformatics.

Source

Journal of the American Society for Information Science and Technology. 56(2005) no.5, S.440-446

Year

2005

Abstract

Bioinformatics is a multifaceted discipline combining many scientific fields including computational biology, statistics, mathematics, molecular biology, and genetics. Bioinformatics enables biomedical investigators to exploit existing and emerging computational technologies to seamlessly store, mine, retrieve, and analyze data from genomics and proteomics technologies. This is achieved by creating unified data models, standardizing data interfaces, developing structured vocabularies, generating new data visualization methods, and capturing detailed metadata that describes various aspects of the experimental design and analysis methods. Already there are a number of related undertakings that are dividing the field into more specialized groups. Clinical Bioinformatics and Biomedical Informatics are emerging as transitional fields to promote the utilization of genomics and proteomics data combined with medical history and demographic data towards personalized medicine, molecular diagnostics, pharmacogenomics and predicting outcomes of therapeutic interventions. The field of bioinformatics will continue to evolve through the incorporation of diverse technologies and methodologies that draw experts from disparate fields to create the latest computational and informational tools specifically design for the biomedical research enterprise.

Footnote

Beitrag in einem special issue on bioinformatics

Similar documents (content)

1. Song, M.; Kim, S.Y.; Zhang, G.; Ding, Y.; Chambers, T.: Productivity and influence in bioinformatics : a bibliometric analysis using PubMed central (2014) 0.31

   0.30735478 = sum of:
     0.30735478 = product of:
       1.2806449 = sum of:
         0.05040531 = weight(abstract_txt:field in 1202) [ClassicSimilarity], result of:
           0.05040531 = score(doc=1202,freq=4.0), product of:
             0.071815304 = queryWeight, product of:
               1.1942824 = boost
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.013386614 = queryNorm
             0.7018742 = fieldWeight in 1202, product of:
               2.0 = tf(freq=4.0), with freq of:
                 4.0 = termFreq=4.0
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.078125 = fieldNorm(doc=1202)
         0.076065846 = weight(abstract_txt:emerging in 1202) [ClassicSimilarity], result of:
           0.076065846 = score(doc=1202,freq=2.0), product of:
             0.11904266 = queryWeight, product of:
               1.5376229 = boost
               5.7833843 = idf(docFreq=369, maxDocs=44218)
               0.013386614 = queryNorm
             0.63897973 = fieldWeight in 1202, product of:
               1.4142135 = tf(freq=2.0), with freq of:
                 2.0 = termFreq=2.0
               5.7833843 = idf(docFreq=369, maxDocs=44218)
               0.078125 = fieldNorm(doc=1202)
         0.19362877 = weight(abstract_txt:genomics in 1202) [ClassicSimilarity], result of:
           0.19362877 = score(doc=1202,freq=1.0), product of:
             0.27961862 = queryWeight, product of:
               2.3565767 = boost
               8.863674 = idf(docFreq=16, maxDocs=44218)
               0.013386614 = queryNorm
             0.69247454 = fieldWeight in 1202, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               8.863674 = idf(docFreq=16, maxDocs=44218)
               0.078125 = fieldNorm(doc=1202)
         0.053656753 = weight(abstract_txt:data in 1202) [ClassicSimilarity], result of:
           0.053656753 = score(doc=1202,freq=3.0), product of:
             0.11885088 = queryWeight, product of:
               2.661095 = boost
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.013386614 = queryNorm
             0.4514628 = fieldWeight in 1202, product of:
               1.7320508 = tf(freq=3.0), with freq of:
                 3.0 = termFreq=3.0
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.078125 = fieldNorm(doc=1202)
         0.15133949 = weight(abstract_txt:biomedical in 1202) [ClassicSimilarity], result of:
           0.15133949 = score(doc=1202,freq=1.0), product of:
             0.2715927 = queryWeight, product of:
               2.8444822 = boost
               7.132539 = idf(docFreq=95, maxDocs=44218)
               0.013386614 = queryNorm
             0.5572296 = fieldWeight in 1202, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               7.132539 = idf(docFreq=95, maxDocs=44218)
               0.078125 = fieldNorm(doc=1202)
         0.75554866 = weight(abstract_txt:bioinformatics in 1202) [ClassicSimilarity], result of:
           0.75554866 = score(doc=1202,freq=3.0), product of:
             0.65217984 = queryWeight, product of:
               5.6905236 = boost
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.013386614 = queryNorm
             1.1584975 = fieldWeight in 1202, product of:
               1.7320508 = tf(freq=3.0), with freq of:
                 3.0 = termFreq=3.0
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.078125 = fieldNorm(doc=1202)
       0.24 = coord(6/25)
   

2. Jonkers, K.; Moya Anegon, F. de; Aguillo, I.F.: Measuring the usage of e-research infrastructure as an indicator of research activity (2012) 0.25

   0.24771677 = sum of:
     0.24771677 = product of:
       0.88470274 = sum of:
         0.019826803 = weight(abstract_txt:methods in 277) [ClassicSimilarity], result of:
           0.019826803 = score(doc=277,freq=1.0), product of:
             0.06120045 = queryWeight, product of:
               1.102493 = boost
               4.146752 = idf(docFreq=1900, maxDocs=44218)
               0.013386614 = queryNorm
             0.32396498 = fieldWeight in 277, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               4.146752 = idf(docFreq=1900, maxDocs=44218)
               0.078125 = fieldNorm(doc=277)
         0.025202654 = weight(abstract_txt:field in 277) [ClassicSimilarity], result of:
           0.025202654 = score(doc=277,freq=1.0), product of:
             0.071815304 = queryWeight, product of:
               1.1942824 = boost
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.013386614 = queryNorm
             0.3509371 = fieldWeight in 277, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.078125 = fieldNorm(doc=277)
         0.10331682 = weight(abstract_txt:genetics in 277) [ClassicSimilarity], result of:
           0.10331682 = score(doc=277,freq=1.0), product of:
             0.14600134 = queryWeight, product of:
               1.2040983 = boost
               9.05783 = idf(docFreq=13, maxDocs=44218)
               0.013386614 = queryNorm
             0.707643 = fieldWeight in 277, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               9.05783 = idf(docFreq=13, maxDocs=44218)
               0.078125 = fieldNorm(doc=277)
         0.10002052 = weight(abstract_txt:biology in 277) [ClassicSimilarity], result of:
           0.10002052 = score(doc=277,freq=1.0), product of:
             0.18001646 = queryWeight, product of:
               1.8908395 = boost
               7.11192 = idf(docFreq=97, maxDocs=44218)
               0.013386614 = queryNorm
             0.55561876 = fieldWeight in 277, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               7.11192 = idf(docFreq=97, maxDocs=44218)
               0.078125 = fieldNorm(doc=277)
         0.053117227 = weight(abstract_txt:fields in 277) [ClassicSimilarity], result of:
           0.053117227 = score(doc=277,freq=1.0), product of:
             0.13513675 = queryWeight, product of:
               2.0064619 = boost
               5.0312033 = idf(docFreq=784, maxDocs=44218)
               0.013386614 = queryNorm
             0.39306277 = fieldWeight in 277, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               5.0312033 = idf(docFreq=784, maxDocs=44218)
               0.078125 = fieldNorm(doc=277)
         0.1470025 = weight(abstract_txt:molecular in 277) [ClassicSimilarity], result of:
           0.1470025 = score(doc=277,freq=1.0), product of:
             0.23270336 = queryWeight, product of:
               2.149809 = boost
               8.085969 = idf(docFreq=36, maxDocs=44218)
               0.013386614 = queryNorm
             0.6317163 = fieldWeight in 277, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               8.085969 = idf(docFreq=36, maxDocs=44218)
               0.078125 = fieldNorm(doc=277)
         0.43621624 = weight(abstract_txt:bioinformatics in 277) [ClassicSimilarity], result of:
           0.43621624 = score(doc=277,freq=1.0), product of:
             0.65217984 = queryWeight, product of:
               5.6905236 = boost
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.013386614 = queryNorm
             0.6688588 = fieldWeight in 277, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.078125 = fieldNorm(doc=277)
       0.28 = coord(7/25)
   

3. Toldo, L.; Rippmann, F.: Integrated bioinformatics application for automated target discovery. (2005) 0.18

   0.17699939 = sum of:
     0.17699939 = product of:
       0.88499695 = sum of:
         0.019826803 = weight(abstract_txt:methods in 5260) [ClassicSimilarity], result of:
           0.019826803 = score(doc=5260,freq=1.0), product of:
             0.06120045 = queryWeight, product of:
               1.102493 = boost
               4.146752 = idf(docFreq=1900, maxDocs=44218)
               0.013386614 = queryNorm
             0.32396498 = fieldWeight in 5260, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               4.146752 = idf(docFreq=1900, maxDocs=44218)
               0.078125 = fieldNorm(doc=5260)
         0.053117227 = weight(abstract_txt:fields in 5260) [ClassicSimilarity], result of:
           0.053117227 = score(doc=5260,freq=1.0), product of:
             0.13513675 = queryWeight, product of:
               2.0064619 = boost
               5.0312033 = idf(docFreq=784, maxDocs=44218)
               0.013386614 = queryNorm
             0.39306277 = fieldWeight in 5260, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               5.0312033 = idf(docFreq=784, maxDocs=44218)
               0.078125 = fieldNorm(doc=5260)
         0.043810554 = weight(abstract_txt:data in 5260) [ClassicSimilarity], result of:
           0.043810554 = score(doc=5260,freq=2.0), product of:
             0.11885088 = queryWeight, product of:
               2.661095 = boost
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.013386614 = queryNorm
             0.36861783 = fieldWeight in 5260, product of:
               1.4142135 = tf(freq=2.0), with freq of:
                 2.0 = termFreq=2.0
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.078125 = fieldNorm(doc=5260)
         0.15133949 = weight(abstract_txt:biomedical in 5260) [ClassicSimilarity], result of:
           0.15133949 = score(doc=5260,freq=1.0), product of:
             0.2715927 = queryWeight, product of:
               2.8444822 = boost
               7.132539 = idf(docFreq=95, maxDocs=44218)
               0.013386614 = queryNorm
             0.5572296 = fieldWeight in 5260, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               7.132539 = idf(docFreq=95, maxDocs=44218)
               0.078125 = fieldNorm(doc=5260)
         0.6169029 = weight(abstract_txt:bioinformatics in 5260) [ClassicSimilarity], result of:
           0.6169029 = score(doc=5260,freq=2.0), product of:
             0.65217984 = queryWeight, product of:
               5.6905236 = boost
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.013386614 = queryNorm
             0.94590914 = fieldWeight in 5260, product of:
               1.4142135 = tf(freq=2.0), with freq of:
                 2.0 = termFreq=2.0
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.078125 = fieldNorm(doc=5260)
       0.2 = coord(5/25)
   

4. Shachak, A.; Fine, S.: ¬The Effect of training on biologists acceptance of bioinformatics tools : a field experiment (2008) 0.17

   0.16815202 = sum of:
     0.16815202 = product of:
       1.0509502 = sum of:
         0.018960433 = weight(abstract_txt:design in 1606) [ClassicSimilarity], result of:
           0.018960433 = score(doc=1606,freq=2.0), product of:
             0.054711886 = queryWeight, product of:
               1.0424119 = boost
               3.9207718 = idf(docFreq=2382, maxDocs=44218)
               0.013386614 = queryNorm
             0.34655052 = fieldWeight in 1606, product of:
               1.4142135 = tf(freq=2.0), with freq of:
                 2.0 = termFreq=2.0
               3.9207718 = idf(docFreq=2382, maxDocs=44218)
               0.0625 = fieldNorm(doc=1606)
         0.020162124 = weight(abstract_txt:field in 1606) [ClassicSimilarity], result of:
           0.020162124 = score(doc=1606,freq=1.0), product of:
             0.071815304 = queryWeight, product of:
               1.1942824 = boost
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.013386614 = queryNorm
             0.28074968 = fieldWeight in 1606, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.0625 = fieldNorm(doc=1606)
         0.024782993 = weight(abstract_txt:data in 1606) [ClassicSimilarity], result of:
           0.024782993 = score(doc=1606,freq=1.0), product of:
             0.11885088 = queryWeight, product of:
               2.661095 = boost
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.013386614 = queryNorm
             0.20852174 = fieldWeight in 1606, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.0625 = fieldNorm(doc=1606)
         0.98704463 = weight(abstract_txt:bioinformatics in 1606) [ClassicSimilarity], result of:
           0.98704463 = score(doc=1606,freq=8.0), product of:
             0.65217984 = queryWeight, product of:
               5.6905236 = boost
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.013386614 = queryNorm
             1.5134547 = fieldWeight in 1606, product of:
               2.828427 = tf(freq=8.0), with freq of:
                 8.0 = termFreq=8.0
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.0625 = fieldNorm(doc=1606)
       0.16 = coord(4/25)
   

5. Huang, H.; Andrews, J.; Tang, J.: Citation characterization and impact normalization in bioinformatics journals (2012) 0.15

   0.15014923 = sum of:
     0.15014923 = product of:
       0.9384327 = sum of:
         0.020162124 = weight(abstract_txt:field in 69) [ClassicSimilarity], result of:
           0.020162124 = score(doc=69,freq=1.0), product of:
             0.071815304 = queryWeight, product of:
               1.1942824 = boost
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.013386614 = queryNorm
             0.28074968 = fieldWeight in 69, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               4.491995 = idf(docFreq=1345, maxDocs=44218)
               0.0625 = fieldNorm(doc=69)
         0.1131603 = weight(abstract_txt:biology in 69) [ClassicSimilarity], result of:
           0.1131603 = score(doc=69,freq=2.0), product of:
             0.18001646 = queryWeight, product of:
               1.8908395 = boost
               7.11192 = idf(docFreq=97, maxDocs=44218)
               0.013386614 = queryNorm
             0.62861085 = fieldWeight in 69, product of:
               1.4142135 = tf(freq=2.0), with freq of:
                 2.0 = termFreq=2.0
               7.11192 = idf(docFreq=97, maxDocs=44218)
               0.0625 = fieldNorm(doc=69)
         0.024782993 = weight(abstract_txt:data in 69) [ClassicSimilarity], result of:
           0.024782993 = score(doc=69,freq=1.0), product of:
             0.11885088 = queryWeight, product of:
               2.661095 = boost
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.013386614 = queryNorm
             0.20852174 = fieldWeight in 69, product of:
               1.0 = tf(freq=1.0), with freq of:
                 1.0 = termFreq=1.0
               3.3363478 = idf(docFreq=4274, maxDocs=44218)
               0.0625 = fieldNorm(doc=69)
         0.7803273 = weight(abstract_txt:bioinformatics in 69) [ClassicSimilarity], result of:
           0.7803273 = score(doc=69,freq=5.0), product of:
             0.65217984 = queryWeight, product of:
               5.6905236 = boost
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.013386614 = queryNorm
             1.196491 = fieldWeight in 69, product of:
               2.236068 = tf(freq=5.0), with freq of:
                 5.0 = termFreq=5.0
               8.561393 = idf(docFreq=22, maxDocs=44218)
               0.0625 = fieldNorm(doc=69)
       0.16 = coord(4/25)